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  • MSK-IMPACT Clinical Sequencing Cohort (MSKCC, Nat Med 2017): Targeted sequencing of 10,000 clinical cases using the MSK-IMPACT assay

    Description

    This dataset contains summary data visualizations and clinical data from the targeted sequencing of 10,000 clinical cases using the MSK-IMPACT assay. The clinical data includes mutation count, information about mutated genes, tumor mutational burden calculations, tissue site from which the sample was derived, tumor purity among other relevant data points. The data set also includes copy-number segment...

    Subject
    Adenocarcinoma
    Adenocarcinoma of Lung
    Adenocarcinoma, Mucinous
    Breast Neoplasms
    Carcinoma, Ductal, Breast
    Carcinoma, Hepatocellular
    Carcinoma, Lobular
    Carcinoma, Non-Small-Cell Lung
    Carcinoma, Renal Cell
    Carcinoma, Squamous Cell
    Carcinosarcoma
    Cholangiocarcinoma
    Colonic Neoplasms
    Colorectal Neoplasms
    Cystadenocarcinoma, Serous
    DNA Mutational Analysis
    Gallbladder Neoplasms
    Glioblastoma
    Liposarcoma
    Lung Neoplasms
    Lymphoma, Follicular
    Melanoma
    Mesothelioma
    Neoplasms, Squamous Cell
    Neurofibroma
    Oligodendroglioma
    Osteosarcoma
    Ovarian Neoplasms
    Pancreatic Neoplasms
    Prostatic Neoplasms
    Rectal Neoplasms
    Sarcoma
    Sarcoma, Synovial
    Squamous Cell Carcinoma of Head and Neck
    Stomach Neoplasms
    Thyroid Cancer, Papillary
    Urinary Bladder Neoplasms
    Uterine Neoplasms
    Uveal Neoplasms
    Access Rights
    Free to All
  • Gallbladder Cancer (MSK, Cancer 2018): Targeted Sequencing of 103 samples with matched normals from 101 Gallbladder cancer patients.

    Description

    This dataset contains summary data visualizations and clinical data from a sampling of gallbladder tumors. The clinical data includes deidentified patient and sample IDs, mutation count, the fraction of genome that was altered, patient demographics, sample site, MSK IMPACT gene panel, Center of sequencing, Collaboration Id, Gallbladder Stone , Gene Panel, Metastatic Site, Oncotree Code, Primary Tumor...

    Subject
    DNA Mutational Analysis
    Gallbladder Neoplasms
    Access Rights
    Free to All
  • Distinct Mutational Patterns of Infection and Non-Infection-Related Bile Duct Cancers Revealed by Exome Sequencing (Genome variation profiling by SNP array)

    Authors
    Chan-On, Waraporn
    Cutcutache, Ioana
    Teh, Bin Tean
    Description

    From GEO summary: The impact of different carcinogenic exposures on the specific patterns of somatic mutations in human tumors remains unclear. To clarify this issue, we profiled 209 cholangiocarcinomas (CCAs) from Asia and Europe, including 108 cases caused by liver fluke Opisthorchis viverrini (OV)-infection and 101 cases due to non-OV etiologies. Whole-exome (N = 15) and prevalence screening (N...

    Subject
    Bile Duct Neoplasms
    Cholangiocarcinoma
    Gallbladder Neoplasms
    Access Rights
    Free to All
  • Distinct Mutational Patterns of Infection and Non-Infection-Related Bile Duct Cancers Revealed by Exome Sequencing (methylation profiling array)

    Authors
    Chan-On, Waraporn
    Lim, Weng Khong
    Teh, Bin Tean
    Description

    From GEO Summary: The impact of different carcinogenic exposures on the specific patterns of somatic mutations in human tumors remains unclear. To clarify this issue, we profiled 209 cholangiocarcinomas (CCAs) from Asia and Europe, including 108 cases caused by liver fluke Opisthorchis viverrini (OV)-infection and 101 cases due to non-OV etiologies. Whole-exome (N = 15) and prevalence screening (N...

    Subject
    Bile Duct Neoplasms
    Cholangiocarcinoma
    DNA Methylation
    Gallbladder Neoplasms
    Access Rights
    Free to All
  • Gallbladder Carcinoma (Shanghai, Nat Genet 2014): Whole exome sequencing of 32 gallbladder carcinoma tumor/normal pairs.

    Description

    This dataset contains summary data visualizations and clinical data from a sampling of gallbladder carcinoma tumors. The clinical data includes deidentified patient and sample IDs, mutation count, patient demographics (age and gender) and survival status, presence of ErbB Pathway Mutation, presence of gallbladder stone, presence of jaundice, presence of lymph nodes metastasis, presence of perineural...

    Subject
    DNA Mutational Analysis
    Gallbladder Neoplasms
    Access Rights
    Free to All
  • Distinct Mutational Patterns of Infection and Non-Infection-Related Bile Duct Cancers Revealed by Exome Sequencing

    Description

    Whole Exome Sequencing of 16 non-liver fluke (OV) associated cholangiocarcinomas. Study conducted by Duke NUS Medical School in Singapore containg 471 sequence runs.

    Subject
    Bile Duct Neoplasms
    Cholangiocarcinoma
    Gallbladder Neoplasms
    Access Rights
    Free to All